Pharmacokinetics/Pharmacodynamics Modeler Scientist (M/F)
Chilly-Mazarin, France
il y a 18h

Drug Metabolism & Pharmacokinetics (DMPK) Research Platform in France, is enhancing the development of modeling approaches to drive projects for key decision making.

As a member of the PK group the individual will provide pharmacokinetic expertise and PK / PD support to projects across multiple therapeutic areas, mainly Oncology.

The scope of project responsibility will range from early discovery up to first in human clinical trials.

The candidate will be responsible for :

  • Applying the modeling strategy defined up to the first In Human.
  • Developing mechanism-based PK / PD, population PK / PD and PBPK model and performing evaluation & applications (simulation and extrapolation)
  • Performing extrapolation to humans using appropriate models for informed conclusion and decision making in project teams.
  • Presenting PKPD / PBPK activities within DMPK, and to internal / external experts in the field as well as in international conferences with posters / publications.
  • Contributing to global workstream for the improvement of modeling tools and methodological development
  • Education and experience requested :

  • A Ph.D. in Pharmacokinetics, PKPD / PBPK modeling, Pharmaceutical Sciences, Pharmacology, or related field with a specific focus on pharmacokinetics
  • At least 3 years pharmaceutical industry experience in the conduct of pharmacokinetics and PK / PD support
  • Advanced levels of using Monolix or Nonmem software. Experience in R and knowledge of MATLAB is also preferred. A good knowledge of SimCYP (PBPK software) is an asset.
  • Experience in performing modeling and simulation for preclinical setting is an asset as well as a good knowledge in Oncology and Immuno-Oncology
  • Flexibility is mandatory, the candidate must be able to adapt in a dynamic research environment
  • Good communication and presentation skills.
  • At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers.

    We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

    As part of its diversity commitment, Sanofi is welcoming and integrating people with disabilities.

    Signaler cette offre d'emploi

    Thank you for reporting this job!

    Your feedback will help us improve the quality of our services.

    Mon email
    En cliquant sur « Continuer », je consens au traitement de mes données et à recevoir des alertes email, tel que détaillé dans la Politique de confidentialité de neuvoo. Je peux retirer mon consentement ou me désinscrire à tout moment.
    Formulaire de candidature