Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail.
Sanofi’s Immuno-Oncology Therapeutic Area based in Vitry-sur-Seine, France, is seeking a highly qualified and motivated Principal scientist, PhD with significant experience in Immunology to deliver innovative approaches targeting cross-talk between innate immunity and adaptive immune cells within the tumour microenvironment.
The candidate will lead and manage team of scientists (technicians and cadre) supporting and delivering on drug discovery programs in immuno oncology.
The candidate will serve as an experienced scientist for Immunology-Oncology, guiding the research and ensuring its successful execution while supporting talent development as a mentor and role model.
The candidate will collaborate with Immuno-Oncology Research Therapeutic Area and partner functions.
Manage 2-3 direct reports with a lead by example attitude
Lead cross functional project team to support immune-oncology projects from early conception to early development
Define and execute IO target identification, validation and functional genomics approaches
Identify resources and manage work to design and execute cell-based assays and immune cells genome editing, in vitro assays for target validation and pharmacology studies
Contribute actively in the laboratory to develop and implement new in vitro immune cell assays for target validation, drug activity evaluation and deep mechanistic understanding of new therapeutic approaches
Be an idea generator and advance cutting-edge science to enable continual innovation
Keep up to date with developments in the field, including basic research, clinical development, and competitive landscape
Communicate with managers and other collaborators in an open and effective manner
Provide and promote support for operational procedures according to Sanofi values, ethics and security
Advance research that underpins high-profile publications, presentations and patents
Identify and develop collaborations with academic and industrial partners
JOB-HOLDER ENTRY REQUIREMENTS
PhD in Immuno-Oncology and international postdoc with very good track record of publications
Experience & knowledge
3+ years of experience in transversal / hierarchical management, prior biotech / pharma experience welcome
Understanding of Research and drug development process
Cutting-edge expertise and depth of knowledge in Immuno-Oncology drug development
Extensive cell-based assay development with a variety of readout including flow cytometry, cytokine profiling and functional assays
Hands-on experience in isolation and immune phenotyping of human and / or mouse immune cell populations
Familiar with genome engineering techniques
Strong team player with excellent oral and written communication, cooperate transversally in complex environments
Dynamic, science driven, pro-active and impactful behaviour
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers.
We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
As part of its diversity commitment, Sanofi is welcoming and integrating people with disabilities.